Senior Conjugation Scientist
Created by on 11/23/2022 1:50:14 PM

Job Title: Senior Conjugation Scientist

Reports to: CTO

Start Date: March/April 2023

Hours of Work: Full-time or 80% Part-Time

Salary: £50-60k PA

Please send your CV and a cover letter explaining what you can bring to MediSieve to

The Opportunity

Imagine a world where doctors are able to target and remove infected cells, pathogens, toxins, or even viruses directly from a patient’s bloodstream. At MediSieve we are working towards bringing this dream into a reality. Our Magnetic Blood Filtration System is a device-therapeutic combination that filters harmful substances from the bloodstream using magnetic forces.

If you’ve always dreamt of making a global impact, MediSieve is the place to be! The platform nature of our technology enables us to make a difference in treating humanity's most serious diseases, with the first product targeting hyperinflammation in conditions such as COVID-19 and new products in the pipeline in gene therapy applications.

As a Senior Conjugation Scientist your main objective will be to lead the development of conjugation strategies for our magnetic bead products. This will include developing new conjugation methods (e.g. literature search, drafting protocols, etc), performing conjugations, testing performance and defining the formulation of the final product. You will be involved in the whole life-cycle of the product. You will work closely with the Implementation and Biocompatibility teams to help define the characteristics of the final product to use in the clinic.  

Your day to day will require both project management (supplier management, allocation of resources, risk analysis, etc), and hands-on lab work. You will be expected to manage and contribute to the design and development of new products, as well as hands-on lab work. You will be expected to perform the necessary data analysis and interpretation and produce reports.


What You’ll Be Responsible for

  • Management of a team (initially 1 direct report).
  • Conjugation, purification and characterization of new Bead products.
  • Development and optimization of novel conjugation methodologies.
  • Creating product dashboards and reports.
  • Partner with colleagues on laboratory maintenance, including maintenance of equipment and lab safety.


What We Look for in a Candidate

  • Relevant Science degree (e.g. Biochemistry, Chemistry, Bioengineering).
  • Extensive conjugation/bioconjugation experience (5+ years).
  • Funtionalisation of beads knowledge/working experience.
  • Data analysis and interpretation experience.
  • Demonstrated experience in optimizing/troubleshooting protocols.
  • People Management (experience with at least 1 direct report).
  • Excellent written and verbal communication skills and effective presentation of complex. scientific data.


Not Essential, but Helpful

  • Magnetic Bead knowledge/working experience.
  • Knowledge of biological interactions and/or binding kinetics to substrates.
  • Hands-on experience with immunoassays (e.g. ELISA), including method development.
  • Knowledge/work experience with viral vectors.
  • Medical device or IVD development background.
  • Haematology/blood interaction with beads or devices.
  • Working under an ISO13485 QMS.


You’ll Love This Job if You Are:

  • Proactive
  • Self-motivated
  • Enthusiastic about our mission
  • Adaptable
  • Team-oriented, fun and have excellent interpersonal skills



  • Hybrid working conditions
  • 3% Company pension
  • 25 days holiday
  • Share options scheme
  • A vibrant community of Imperial College’s Translation & Innovation Hub

Diversity Commitment: We believe that diversity enables us to see situations from different points of view, leading to ideas and insights which would otherwise be missed. We are focused on building an inclusive team of people of all backgrounds, experiences, abilities, and perspectives. We are diverse in gender (58% women), origin (6 nationalities) and economic background. Everyone is welcome — there will be no judgement towards things that make you You!

Apply Now

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Latest News

MediSieve Announces Positive Final Results from Phase 1 Clinical Trial of its Magnetic Blood Filtration Platform

MediSieve Announces Positive Final Results from Phase 1 Clinical Trial of its Magnetic Blood Filtration Platform
December 07, 2022

Magnetic Blood Filtration Platform shown to be safe and well tolerated, with no serious adverse events. Investigators recommend further development of the Platform, which has a range of potential clinical applications in inflammation, oncology, gene therapies and others. ...
MediSieve Announces First Volunteer Successfully Enrolled in Phase 1 Clinical Study

MediSieve Announces First Volunteer Successfully Enrolled in Phase 1 Clinical Study
July 08, 2022

Radboud University Medical Center is Conducting Safety Evaluation of MediSieve’s Magnetic Haemofiltration System for the Treatment of Acute Hyperinflammation.